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Preclinical and clinical studies for transplant tolerance via the mixed chimerism approach
Based upon observations in murine models, we have developed protocols to induce renal allograft tolerance by combined kidney and bone marrow transplantation (CKBMT) in non-human primates (NHP) and in humans. Induction of persistent mixed chimerism has proved to be extremely difficult in major histoc...
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| Veröffentlicht in: | Hum Immunol |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5963722/ https://ncbi.nlm.nih.gov/pubmed/29175110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2017.11.008 |
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