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Preclinical and clinical studies for transplant tolerance via the mixed chimerism approach

Based upon observations in murine models, we have developed protocols to induce renal allograft tolerance by combined kidney and bone marrow transplantation (CKBMT) in non-human primates (NHP) and in humans. Induction of persistent mixed chimerism has proved to be extremely difficult in major histoc...

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Podrobná bibliografie
Vydáno v:Hum Immunol
Hlavní autoři: Sasaki, Hajime, Oura, Tetsu, Spitzer, Thomas R., Chen, Yi-Bin, Madsen, Joren C., Allan, James, Sachs, David H., Cosimi, A.B., Kawai, Tatsuo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963722/
https://ncbi.nlm.nih.gov/pubmed/29175110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2017.11.008
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