Preclinical and clinical studies for transplant tolerance via the mixed chimerism approach

Based upon observations in murine models, we have developed protocols to induce renal allograft tolerance by combined kidney and bone marrow transplantation (CKBMT) in non-human primates (NHP) and in humans. Induction of persistent mixed chimerism has proved to be extremely difficult in major histoc...

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Bibliografski detalji
Izdano u:Hum Immunol
Glavni autori: Sasaki, Hajime, Oura, Tetsu, Spitzer, Thomas R., Chen, Yi-Bin, Madsen, Joren C., Allan, James, Sachs, David H., Cosimi, A.B., Kawai, Tatsuo
Format: Artigo
Jezik:Inglês
Izdano: 2017
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963722/
https://ncbi.nlm.nih.gov/pubmed/29175110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2017.11.008
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