Preclinical and clinical studies for transplant tolerance via the mixed chimerism approach

Based upon observations in murine models, we have developed protocols to induce renal allograft tolerance by combined kidney and bone marrow transplantation (CKBMT) in non-human primates (NHP) and in humans. Induction of persistent mixed chimerism has proved to be extremely difficult in major histoc...

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Publicat a:Hum Immunol
Autors principals: Sasaki, Hajime, Oura, Tetsu, Spitzer, Thomas R., Chen, Yi-Bin, Madsen, Joren C., Allan, James, Sachs, David H., Cosimi, A.B., Kawai, Tatsuo
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963722/
https://ncbi.nlm.nih.gov/pubmed/29175110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2017.11.008
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