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Induced regulatory T cells in allograft tolerance via transient mixed chimerism

Successful induction of allograft tolerance has been achieved in nonhuman primates (NHPs) and humans via induction of transient hematopoietic chimerism. Since allograft tolerance was achieved in these recipients without durable chimerism, peripheral mechanisms are postulated to play a major role. He...

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Publicado en:JCI Insight
Main Authors: Hotta, Kiyohiko, Aoyama, Akihiro, Oura, Tetsu, Yamada, Yohei, Tonsho, Makoto, Huh, Kyu Ha, Kawai, Kento, Schoenfeld, David, Allan, James S., Madsen, Joren C., Benichou, Gilles, Smith, Rex-Neal, Colvin, Robert B., Sachs, David H., Cosimi, A. Benedict, Kawai, Tatsuo
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951099/
https://ncbi.nlm.nih.gov/pubmed/27446989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.86419
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