Combination of a Histone Deacetylase 6 Inhibitor and a Somatostatin Receptor Agonist Synergistically Reduces Hepatorenal Cystogenesis in an Animal Model of Polycystic Liver Disease

Hepatic cystogenesis in polycystic liver disease (PLD) is associated with abnormalities in multiple cellular processes, including elevated cAMP and overexpression of histone deacetylase 6 (HDAC6). Disease progression in polycystic kidney (PCK) rats (an animal model of PLD) is attenuated by inhibitio...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Am J Pathol
Autores principales: Lorenzo Pisarello, Maria, Masyuk, Tatyana V., Gradilone, Sergio A., Masyuk, Anatoliy I., Ding, Jingyi F., Lee, Pui-Yuen, LaRusso, Nicholas F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2018
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963486/
https://ncbi.nlm.nih.gov/pubmed/29366679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.12.016
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares