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Combination of a Histone Deacetylase 6 Inhibitor and a Somatostatin Receptor Agonist Synergistically Reduces Hepatorenal Cystogenesis in an Animal Model of Polycystic Liver Disease

Hepatic cystogenesis in polycystic liver disease (PLD) is associated with abnormalities in multiple cellular processes, including elevated cAMP and overexpression of histone deacetylase 6 (HDAC6). Disease progression in polycystic kidney (PCK) rats (an animal model of PLD) is attenuated by inhibitio...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Pathol
Egile Nagusiak: Lorenzo Pisarello, Maria, Masyuk, Tatyana V., Gradilone, Sergio A., Masyuk, Anatoliy I., Ding, Jingyi F., Lee, Pui-Yuen, LaRusso, Nicholas F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Investigative Pathology 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963486/
https://ncbi.nlm.nih.gov/pubmed/29366679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.12.016
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