Combination of a Histone Deacetylase 6 Inhibitor and a Somatostatin Receptor Agonist Synergistically Reduces Hepatorenal Cystogenesis in an Animal Model of Polycystic Liver Disease

Hepatic cystogenesis in polycystic liver disease (PLD) is associated with abnormalities in multiple cellular processes, including elevated cAMP and overexpression of histone deacetylase 6 (HDAC6). Disease progression in polycystic kidney (PCK) rats (an animal model of PLD) is attenuated by inhibitio...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Lorenzo Pisarello, Maria, Masyuk, Tatyana V., Gradilone, Sergio A., Masyuk, Anatoliy I., Ding, Jingyi F., Lee, Pui-Yuen, LaRusso, Nicholas F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963486/
https://ncbi.nlm.nih.gov/pubmed/29366679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.12.016
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados