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HDAC6 Is Overexpressed in Cystic Cholangiocytes and Its Inhibition Reduces Cystogenesis

Polycystic liver disease (PLD) is a member of the cholangiopathies, a group of liver diseases in which cholangiocytes, the epithelia lining of the biliary tree, are the target cells. PLDs are caused by mutations in genes involved in intracellular signaling pathways, cell cycle regulation, and ciliog...

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Detalhes bibliográficos
Main Authors: Gradilone, Sergio A., Habringer, Stefan, Masyuk, Tatyana V., Howard, Brynn N., Masyuk, Anatoliy I., LaRusso, Nicholas F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936326/
https://ncbi.nlm.nih.gov/pubmed/24434010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.11.027
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