Deletion of the imprinted gene, Grb10, promotes hematopoietic stem cell self-renewal and regeneration

Imprinted genes are differentially expressed by adult stem cells, but their functions in regulating adult stem cell fate are incompletely understood. Here, we show that growth factor receptor bound protein 10 (Grb10), an imprinted gene, regulates hematopoietic stem cell (HSC) self-renewal and regene...

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Vydáno v:Cell Rep
Hlavní autoři: Yan, Xiao, Himburg, Heather A., Pohl, Katherine, Quarmyne, Mamle, Tran, Evelyn, Zhang, Yurun, Fang, Tiancheng, Kan, Jenny, Chao, Nelson J., Zhao, Liman, Doan, Phuong L., Chute, John P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963255/
https://ncbi.nlm.nih.gov/pubmed/27806297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.10.025
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