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Epidermal growth factor receptor–dependent DNA repair promotes murine and human hematopoietic regeneration
Chemotherapy and irradiation cause DNA damage to hematopoietic stem cells (HSCs), leading to HSC depletion and dysfunction and the risk of malignant transformation over time. Extrinsic regulation of HSC DNA repair is not well understood, and therapies to augment HSC DNA repair following myelosuppres...
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| Publicado no: | Blood |
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| Main Authors: | , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7378456/ https://ncbi.nlm.nih.gov/pubmed/32369572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020005895 |
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