Deletion of the imprinted gene, Grb10, promotes hematopoietic stem cell self-renewal and regeneration

Imprinted genes are differentially expressed by adult stem cells, but their functions in regulating adult stem cell fate are incompletely understood. Here, we show that growth factor receptor bound protein 10 (Grb10), an imprinted gene, regulates hematopoietic stem cell (HSC) self-renewal and regene...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Yan, Xiao, Himburg, Heather A., Pohl, Katherine, Quarmyne, Mamle, Tran, Evelyn, Zhang, Yurun, Fang, Tiancheng, Kan, Jenny, Chao, Nelson J., Zhao, Liman, Doan, Phuong L., Chute, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963255/
https://ncbi.nlm.nih.gov/pubmed/27806297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.10.025
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