Deletion of the imprinted gene, Grb10, promotes hematopoietic stem cell self-renewal and regeneration

Imprinted genes are differentially expressed by adult stem cells, but their functions in regulating adult stem cell fate are incompletely understood. Here, we show that growth factor receptor bound protein 10 (Grb10), an imprinted gene, regulates hematopoietic stem cell (HSC) self-renewal and regene...

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Publicado en:Cell Rep
Main Authors: Yan, Xiao, Himburg, Heather A., Pohl, Katherine, Quarmyne, Mamle, Tran, Evelyn, Zhang, Yurun, Fang, Tiancheng, Kan, Jenny, Chao, Nelson J., Zhao, Liman, Doan, Phuong L., Chute, John P.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963255/
https://ncbi.nlm.nih.gov/pubmed/27806297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.10.025
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