PTPσ inhibitors promote hematopoietic stem cell regeneration

Receptor type protein tyrosine phosphatase-sigma (PTPσ) is primarily expressed by adult neurons and regulates neural regeneration. We recently discovered that PTPσ is also expressed by hematopoietic stem cells (HSCs). Here, we describe small molecule inhibitors of PTPσ that promote HSC regeneration...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Zhang, Yurun, Roos, Martina, Himburg, Heather, Termini, Christina M., Quarmyne, Mamle, Li, Michelle, Zhao, Liman, Kan, Jenny, Fang, Tiancheng, Yan, Xiao, Pohl, Katherine, Diers, Emelyne, Jin Gim, Hyo, Damoiseaux, Robert, Whitelegge, Julian, McBride, William, Jung, Michael E., Chute, John P.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694155/
https://ncbi.nlm.nih.gov/pubmed/31413255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11490-5
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares