Neurofibromin Deficiency Induces Endothelial Cell Proliferation and Retinal Neovascularization

PURPOSE: Neurofibromatosis type 1 (NF1) is the result of inherited mutations in the NF1 tumor suppressor gene, which encodes the protein neurofibromin. Eye manifestations are common in NF1 with recent reports describing a vascular dysplasia in the retina and choroid. Common features of NF1 retinopat...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Zhang, Hanfang, Hudson, Farlyn Z., Xu, Zhimin, Tritz, Rebekah, Rojas, Modesto, Patel, Chintan, Haigh, Stephen B., Bordán, Zsuzsanna, Ingram, David A., Fulton, David J., Weintraub, Neal L., Caldwell, Ruth B., Stansfield, Brian K.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2018
Assuntos:
Retina
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963003/
https://ncbi.nlm.nih.gov/pubmed/29847659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-22588
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