Neurofibromin Deficiency Induces Endothelial Cell Proliferation and Retinal Neovascularization

PURPOSE: Neurofibromatosis type 1 (NF1) is the result of inherited mutations in the NF1 tumor suppressor gene, which encodes the protein neurofibromin. Eye manifestations are common in NF1 with recent reports describing a vascular dysplasia in the retina and choroid. Common features of NF1 retinopat...

Full description

Saved in:
Bibliographic Details
Published in:Invest Ophthalmol Vis Sci
Main Authors: Zhang, Hanfang, Hudson, Farlyn Z., Xu, Zhimin, Tritz, Rebekah, Rojas, Modesto, Patel, Chintan, Haigh, Stephen B., Bordán, Zsuzsanna, Ingram, David A., Fulton, David J., Weintraub, Neal L., Caldwell, Ruth B., Stansfield, Brian K.
Format: Artigo
Language:Inglês
Published: The Association for Research in Vision and Ophthalmology 2018
Subjects:
Retina
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963003/
https://ncbi.nlm.nih.gov/pubmed/29847659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-22588
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items