Nf1 Heterozygous Mice Recapitulate the Anthropometric and Metabolic Features of Human Neurofibromatosis Type 1.

Neurofibromatosis type 1 (NF1) is a heritable cancer predisposition syndrome resulting from mutations in the NF1 tumor suppressor gene. Genotype-phenotype correlations for NF1 are rare due to the large number of NF1 mutations and role of modifier genes in manifestations of NF1; however, emerging rep...

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Publicat a:Transl Res
Autors principals: Tritz, Rebekah, Benson, Tyler, Harris, Valerie, Hudson, Farlyn Z., Mintz, James, Zhang, Hanfang, Kennard, Simone, Chen, Weiqin, Stepp, David W., Csanyi, Gabor, de Chantemèle, Eric J. Belin, Weintraub, Neal L., Stansfield, Brian K.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7779711/
https://ncbi.nlm.nih.gov/pubmed/32781282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2020.08.001
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