Heterozygous Mylk3 Knockout Mice Partially Recapitulate Human DCM With Heterozygous MYLK3 Mutations

Backgrounds: Recent studies identified heterozygous variants in MYLK3 gene that encodes cardiac myosin light chain kinase (cMLCK) are related to familial dilated cardiomyopathy (DCM) for the first time. Autosomal dominant traits suggest that pathogenesis of DCM could be related to heterozygous MYLK3...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Physiol
Prif Awduron: Tougas, Carson L., Grindrod, Tabor, Cai, Lawrence X., Alkassis, Fariz F., Kasahara, Hideko
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2019
Pynciau:
Physiology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563786/
https://ncbi.nlm.nih.gov/pubmed/31244672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00696
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