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Heterozygous Mylk3 Knockout Mice Partially Recapitulate Human DCM With Heterozygous MYLK3 Mutations

Backgrounds: Recent studies identified heterozygous variants in MYLK3 gene that encodes cardiac myosin light chain kinase (cMLCK) are related to familial dilated cardiomyopathy (DCM) for the first time. Autosomal dominant traits suggest that pathogenesis of DCM could be related to heterozygous MYLK3...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Physiol
Egile Nagusiak: Tougas, Carson L., Grindrod, Tabor, Cai, Lawrence X., Alkassis, Fariz F., Kasahara, Hideko
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563786/
https://ncbi.nlm.nih.gov/pubmed/31244672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00696
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