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Core features of frontotemporal dementia recapitulated in progranulin knockout mice

Frontotemporal dementia (FTD) is typified by behavioral and cognitive changes manifested as altered social comportment and impaired memory performance. To investigate the neurodegenerative consequences of progranulin gene (GRN) mutations, which cause an inherited form of FTD, we used previously gene...

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Hlavní autoři: Ghoshal, N., Dearborn, J.T., Wozniak, D.F., Cairns, N.J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225509/
https://ncbi.nlm.nih.gov/pubmed/21933710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.08.029
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