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Core features of frontotemporal dementia recapitulated in progranulin knockout mice
Frontotemporal dementia (FTD) is typified by behavioral and cognitive changes manifested as altered social comportment and impaired memory performance. To investigate the neurodegenerative consequences of progranulin gene (GRN) mutations, which cause an inherited form of FTD, we used previously gene...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3225509/ https://ncbi.nlm.nih.gov/pubmed/21933710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.08.029 |
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