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Core features of frontotemporal dementia recapitulated in progranulin knockout mice

Frontotemporal dementia (FTD) is typified by behavioral and cognitive changes manifested as altered social comportment and impaired memory performance. To investigate the neurodegenerative consequences of progranulin gene (GRN) mutations, which cause an inherited form of FTD, we used previously gene...

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Detalhes bibliográficos
Main Authors: Ghoshal, N., Dearborn, J.T., Wozniak, D.F., Cairns, N.J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225509/
https://ncbi.nlm.nih.gov/pubmed/21933710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.08.029
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