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Therapeutic potential of Bcl-x(L)/Mcl-1 synthetic inhibitor JY-1-106 and retinoids for human triple-negative breast cancer treatment

Overexpression of anti-apoptotic proteins belonging to the B cell lymphoma (Bcl)-2 family is observed in numerous cancer types and has been postulated to promote cancer cell survival and chemotherapy resistance. Bcl-extra large (x(L))/myeloid cell leukemia sequence (Mcl)-1 was demonstrated to be exp...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Perri, Mariarita, Yap, Jeremy L., Fletcher, Steven, Cione, Erika, Kane, Maureen A.
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5962833/
https://ncbi.nlm.nih.gov/pubmed/29849791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8258
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