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Robustness of In Vitro Selection Assays of DNA-Encoded Peptidomimetic Ligands to CBX7 and CBX8

The identification of protein ligands from a DNA-encoded library is commonly conducted by an affinity selection assay. These assays are often not validated for robustness, raising questions about selections that fail to identify ligands and the utility of enrichment values for ranking ligand potenci...

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書目詳細資料
發表在:SLAS Discov
Main Authors: Denton, Kyle E., Wang, Sijie, Gignac, Michael C., Milosevich, Natalia, Hof, Fraser, Dykhuizen, Emily C., Krusemark, Casey J.
格式: Artigo
語言:Inglês
出版: 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5962403/
https://ncbi.nlm.nih.gov/pubmed/29309209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555217750871
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