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Crosslinking of DNA-linked ligands to target proteins for enrichment from DNA-encoded libraries()
Achieving sufficient enrichment of ligands from DNA-encoded libraries for detection can be difficult, particularly for low affinity ligands within highly complex libraries. To address this challenge, we present an approach for crosslinking DNA-linked ligands to target proteins using electrophilic or...
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| Publicat a: | Medchemcomm |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5609701/ https://ncbi.nlm.nih.gov/pubmed/28948007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C6MD00288A |
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