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Quantitative Comparison of Enrichment from DNA-Encoded Chemical Library Selections
[Image: see text] DNA-encoded chemical libraries (DELs) provide a high-throughput and cost-effective route for screening billions of unique molecules for binding affinity for diverse protein targets. Identifying candidate compounds from these libraries involves affinity selection, DNA sequencing, an...
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Publicado no: | ACS Comb Sci |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Chemical
Society
2019
|
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6372980/ https://ncbi.nlm.nih.gov/pubmed/30672692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscombsci.8b00116 |
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