Palladium-Catalyzed Hydroxycarbonylation of (Hetero)aryl Halides for DNA-Encoded Chemical Library Synthesis

[Image: see text] A strategy for DNA-compatible, palladium-catalyzed hydroxycarbonylation of (hetero)aryl halides on DNA–chemical conjugates has been developed. This method generally provided the corresponding carboxylic acids in moderate to very good conversions for (hetero)aryl iodides and bromide...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: Li, Jian-Yuan, Miklossy, Gabriella, Modukuri, Ram K., Bohren, Kurt M., Yu, Zhifeng, Palaniappan, Murugesan, Faver, John C., Riehle, Kevin, Matzuk, Martin M., Simmons, Nicholas
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6706801/
https://ncbi.nlm.nih.gov/pubmed/31329429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.9b00447
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