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Identifying OXA-48 Carbapenemase Inhibitors Using DNA-Encoded Chemical Libraries
Bacterial resistance to β-lactam antibiotics is largely mediated by β-lactamases, which catalyze the hydrolysis of these drugs and continue to emerge in response to antibiotic use. β-lactamases that hydrolyze the last resort carbapenem class of β-lactam antibiotics (carbapenemases) are a growing glo...
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| Publicado no: | ACS Infect Dis |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7673237/ https://ncbi.nlm.nih.gov/pubmed/32182432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.0c00015 |
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