Identifying OXA-48 Carbapenemase Inhibitors Using DNA-Encoded Chemical Libraries

Bacterial resistance to β-lactam antibiotics is largely mediated by β-lactamases, which catalyze the hydrolysis of these drugs and continue to emerge in response to antibiotic use. β-lactamases that hydrolyze the last resort carbapenem class of β-lactam antibiotics (carbapenemases) are a growing glo...

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Detaylı Bibliyografya
Yayımlandı:ACS Infect Dis
Asıl Yazarlar: Taylor, Doris Mia, Anglin, Justin, Park, Suhyeorn, Ucisik, Melek N., Faver, John C., Simmons, Nicholas, Jin, Zhuang, Palaniappan, Murugesan, Nyshadham, Pranavanand, Li, Feng, Campbell, James, Hu, Liya, Sankaran, Banumathi, Prasad, B.V. Venkataram, Huang, Hongbing, Matzuk, Martin M., Palzkill, Timothy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7673237/
https://ncbi.nlm.nih.gov/pubmed/32182432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.0c00015
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