Defining the Transcriptional Targets of Leptin Reveals a Role for Atf3 in Leptin Action

Leptin acts via its receptor (LepRb) to modulate gene expression in hypothalamic LepRb-expressing neurons, thereby controlling energy balance and glucose homeostasis. Despite the importance of the control of gene expression in hypothalamic LepRb neurons for leptin action, the transcriptional targets...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Allison, Margaret B., Pan, Warren, MacKenzie, Alexander, Patterson, Christa, Shah, Kimi, Barnes, Tammy, Cheng, Wenwen, Rupp, Alan, Olson, David P., Myers, Martin G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2018
Assuntos:
Obesity Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961413/
https://ncbi.nlm.nih.gov/pubmed/29535089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db17-1395
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