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The full-length cytochrome P450 enzyme CYP102A1 dimerizes at its reductase domains and has flexible heme domains for efficient catalysis

The cytochrome P450 enzyme CYP102A1 from Bacillus megaterium is a highly efficient hydroxylase of fatty acids, and there is a significant interest in using CYP102A1 for biotechnological applications. Here, we used size-exclusion chromatography–multiangle light scattering (SEC–MALS) analysis and nega...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zhang, Haoming, Yokom, Adam L., Cheng, Shen, Su, Min, Hollenberg, Paul F., Southworth, Daniel R., Osawa, Yoichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961045/
https://ncbi.nlm.nih.gov/pubmed/29618513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000600
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