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Orchestrated Domain Movement in Catalysis by Cytochrome P450 Reductase
NADPH-cytochrome P450 reductase is a multi-domain redox enzyme which is a key component of the P450 mono-oxygenase drug-metabolizing system. We report studies of the conformational equilibrium of this enzyme using small-angle neutron scattering, under conditions where we are able to control the redo...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5575293/ https://ncbi.nlm.nih.gov/pubmed/28852004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09840-8 |
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