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Redox-Linked Domain Movements in the Catalytic Cycle of Cytochrome P450 Reductase
NADPH-cytochrome P450 reductase is a key component of the P450 mono-oxygenase drug-metabolizing system. There is evidence for a conformational equilibrium involving large-scale domain motions in this enzyme. We now show, using small-angle X-ray scattering (SAXS) and small-angle neutron scattering, t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3763376/ https://ncbi.nlm.nih.gov/pubmed/23911089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.06.022 |
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