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Drug Combination Synergy in Worm-like Polymeric Micelles Improves Treatment Outcome for Small Cell and Non-Small Cell Lung Cancer

Nanoparticle-based systems for concurrent delivery of multiple drugs can improve outcomes of cancer treatments, but face challenges because of differential solubility and fairly low threshold for incorporation of many drugs. Here we demonstrate that this approach can be used to greatly improve the t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:ACS Nano
Hauptverfasser: Wan, Xiaomeng, Min, Yuanzeng, Bludau, Herdis, Keith, Andrew, Sheiko, Sergei S., Jordan, Rainer, Wang, Andrew Z., Sokolsky-Papkov, Marina, Kabanov, Alexander V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960350/
https://ncbi.nlm.nih.gov/pubmed/29533606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.7b07878
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