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Prevention of MDR Development in Leukemia Cells by Micelle-Forming Polymeric Surfactant

Doxorubicin (Dox) incorporated in nanosized polymeric micelles, SP1049C, has shown promise as monotherapy in patients with advanced esophageal carcinoma. The formulation contains amphiphilic block copolymers, Pluronics, that exhibit unique ability to chemosensitize multidrug resistant (MDR) tumors b...

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Detalhes bibliográficos
Main Authors: Sharma, Amit K, Zhang, Li, Li, Shu, Kelly, David L., Alakhov, Valery Yu., Batrakova, Elena V., Kabanov, Alexander V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711209/
https://ncbi.nlm.nih.gov/pubmed/18722489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2008.07.031
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