Prevention of MDR Development in Leukemia Cells by Micelle-Forming Polymeric Surfactant

Doxorubicin (Dox) incorporated in nanosized polymeric micelles, SP1049C, has shown promise as monotherapy in patients with advanced esophageal carcinoma. The formulation contains amphiphilic block copolymers, Pluronics, that exhibit unique ability to chemosensitize multidrug resistant (MDR) tumors b...

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Hlavní autoři: Sharma, Amit K, Zhang, Li, Li, Shu, Kelly, David L., Alakhov, Valery Yu., Batrakova, Elena V., Kabanov, Alexander V.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711209/
https://ncbi.nlm.nih.gov/pubmed/18722489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2008.07.031
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