Poly(2-oxazoline) based Micelles with High Capacity for 3rd Generation Taxoids: preparation, in vitro and in vivo evaluation

The clinically and commercially successful taxanes, paclitaxel and docetaxel suffer from two major drawbacks, namely their very low aqueous solubility and the risk of developing resistance. Here, we present a method that overcomes both drawbacks in a very simple manner. We formulated 3(rd) generatio...

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Detaylı Bibliyografya
Yayımlandı:J Control Release
Asıl Yazarlar: He, Zhijian, Schulz, Anita, Wan, Xiaomeng, Seitz, Joshua, Bludau, Herdis, Alakhova, Daria Y., Darr, David B., Perou, Charles M., Jordan, Rainer, Ojima, Iwao, Kabanov, Alexander V., Luxenhofer, Robert
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479148/
https://ncbi.nlm.nih.gov/pubmed/25725361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.02.024
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