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Structural basis of arrestin-dependent signal transduction

Arrestins are a small family of proteins with four isoforms in humans. Remarkably, two arrestins regulate signaling from >800 G protein-coupled receptors (GPCRs) or non-receptor activators by simultaneously binding an activator and one out of hundreds of other signaling proteins. When arrestins a...

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Detalles Bibliográficos
Publicado en:Trends Biochem Sci
Main Authors: Chen, Qiuyan, Iverson, T.M., Gurevich, Vsevolod V.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5959776/
https://ncbi.nlm.nih.gov/pubmed/29636212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2018.03.005
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