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Arrestins: Introducing Signaling Bias Into Multifunctional Proteins

Arrestins were discovered as proteins that bind active phosphorylated G protein-coupled receptors (GPCRs) and block their interactions with G proteins, i.e., for their role in homologous desensitization of GPCRs. Mammals express only four arrestin subtypes, two of which are largely restricted to the...

詳細記述

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書誌詳細
出版年:Prog Mol Biol Transl Sci
主要な著者: Gurevich, Vsevolod V., Chen, Qiuyan, Gurevich, Eugenia V.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437759/
https://ncbi.nlm.nih.gov/pubmed/30470292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.pmbts.2018.07.007
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