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Arrestins: Introducing Signaling Bias Into Multifunctional Proteins

Arrestins were discovered as proteins that bind active phosphorylated G protein-coupled receptors (GPCRs) and block their interactions with G proteins, i.e., for their role in homologous desensitization of GPCRs. Mammals express only four arrestin subtypes, two of which are largely restricted to the...

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Detalhes bibliográficos
Publicado no:Prog Mol Biol Transl Sci
Main Authors: Gurevich, Vsevolod V., Chen, Qiuyan, Gurevich, Eugenia V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437759/
https://ncbi.nlm.nih.gov/pubmed/30470292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.pmbts.2018.07.007
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