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Overview of different mechanisms of arrestin-mediated signaling

Arrestins were discovered based on their ability to selectively bind active phosphorylated GPCRs and suppress (arrest) receptor coupling to G proteins. Subsequently non-visual arrestins were shown to be signaling proteins in their own right, activating a variety of cellular pathways. Arrestins are h...

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Detalhes bibliográficos
Publicado no:Curr Protoc Pharmacol
Main Authors: Gurevich, Vsevolod V., Gurevich, Eugenia V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260930/
https://ncbi.nlm.nih.gov/pubmed/25446289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471141755.ph0210s67
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