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Overview of different mechanisms of arrestin-mediated signaling
Arrestins were discovered based on their ability to selectively bind active phosphorylated GPCRs and suppress (arrest) receptor coupling to G proteins. Subsequently non-visual arrestins were shown to be signaling proteins in their own right, activating a variety of cellular pathways. Arrestins are h...
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| Udgivet i: | Curr Protoc Pharmacol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4260930/ https://ncbi.nlm.nih.gov/pubmed/25446289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471141755.ph0210s67 |
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