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Arrestins: Introducing Signaling Bias Into Multifunctional Proteins
Arrestins were discovered as proteins that bind active phosphorylated G protein-coupled receptors (GPCRs) and block their interactions with G proteins, i.e., for their role in homologous desensitization of GPCRs. Mammals express only four arrestin subtypes, two of which are largely restricted to the...
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| Gepubliceerd in: | Prog Mol Biol Transl Sci |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6437759/ https://ncbi.nlm.nih.gov/pubmed/30470292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.pmbts.2018.07.007 |
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