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Arrestins: Introducing Signaling Bias Into Multifunctional Proteins

Arrestins were discovered as proteins that bind active phosphorylated G protein-coupled receptors (GPCRs) and block their interactions with G proteins, i.e., for their role in homologous desensitization of GPCRs. Mammals express only four arrestin subtypes, two of which are largely restricted to the...

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Bibliographische Detailangaben
Veröffentlicht in:Prog Mol Biol Transl Sci
Hauptverfasser: Gurevich, Vsevolod V., Chen, Qiuyan, Gurevich, Eugenia V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437759/
https://ncbi.nlm.nih.gov/pubmed/30470292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.pmbts.2018.07.007
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