A Binding Kinetics Study of Human Adenosine A(3) Receptor Agonists

The human adenosine A(3) (hA(3)) receptor has been suggested as a viable drug target in inflammatory diseases and in cancer. So far, a number of selective hA(3) receptor agonists (e.g. IB-MECA and 2-Cl-IB-MECA) inducing anti-inflammatory or anticancer effects are under clinical investigation. Drug-t...

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Dettagli Bibliografici
Pubblicato in:Biochem Pharmacol
Autori principali: Xia, Lizi, Kyrizaki, Athina, Tosh, Dilip K., van Duijl, Tirsa T., Roorda, Jacomina Cornelia, Jacobson, Kenneth A., IJzerman, Adriaan P., Heitman, Laura H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5959751/
https://ncbi.nlm.nih.gov/pubmed/29305857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2017.12.026
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