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Unified approach for extrapolation and bridging of adult information in early-phase dose-finding paediatric studies
The number of trials conducted and the number of patients per trial are typically small in paediatric clinical studies. This is due to ethical constraints and the complexity of the medical process for treating children. While incorporating prior knowledge from adults may be extremely valuable, this...
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| Publicado no: | Stat Methods Med Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5958415/ https://ncbi.nlm.nih.gov/pubmed/27705884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0962280216671348 |
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