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Designing a Pediatric Study for an Antimalarial Drug by Using Information from Adults
The objectives of this study were to design a pharmacokinetic (PK) study by using information about adults and evaluate the robustness of the recommended design through a case study of mefloquine. PK data about adults and children were available from two different randomized studies of the treatment...
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Pubblicato in: | Antimicrob Agents Chemother |
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Autori principali: | , , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
American Society for Microbiology
2016
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4775938/ https://ncbi.nlm.nih.gov/pubmed/26711749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01125-15 |
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