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Designing a Pediatric Study for an Antimalarial Drug by Using Information from Adults

The objectives of this study were to design a pharmacokinetic (PK) study by using information about adults and evaluate the robustness of the recommended design through a case study of mefloquine. PK data about adults and children were available from two different randomized studies of the treatment...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Petit, Caroline, Jullien, Vincent, Samson, Adeline, Guedj, Jérémie, Kiechel, Jean-René, Zohar, Sarah, Comets, Emmanuelle
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775938/
https://ncbi.nlm.nih.gov/pubmed/26711749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01125-15
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