Delivering two new treatments for malaria: a story of inventive partnerships

Por Diap, Graciela, Olliaro, Piero, Kiechel, Jean-René
Publicado em 2012

The story of artesunate–mefloquine (ASMQ), innovative partnerships in drug development: case study

Por Wells, Susan, Diap, Graciela, Kiechel, Jean-René
Publicado em 2013

Innovative public-private partnerships to maximize the delivery of anti-malarial medicines: lessons learned from the ASAQ Winthrop experience

Por Bompart, François, Kiechel, Jean-René, Sebbag, Robert, Pecoul, Bernard
Publicado em 2011

Population pharmacokinetics of mefloquine, administered as a fixed-dose combination of artesunate-mefloquine in Indian patients for the treatment of acute uncomplicated Plasmodium...

Por Jullien, Vincent, Valecha, Neena, Srivastava, Bina, Sharma, Bhawna, Kiechel, Jean-René
Publicado em 2014

Population Pharmacokinetics and Pharmacodynamic Considerations of Amodiaquine and Desethylamodiaquine in Kenyan Adults with Uncomplicated Malaria Receiving Artesunate-Amodiaquine C...

Por Jullien, Vincent, Ogutu, Bernhards, Juma, Elizabeth, Carn, Gwenaelle, Obonyo, Charles, Kiechel, Jean-René
Publicado em 2010

Designing a Pediatric Study for an Antimalarial Drug by Using Information from Adults

Por Petit, Caroline, Jullien, Vincent, Samson, Adeline, Guedj, Jérémie, Kiechel, Jean-René, Zohar, Sarah, Comets, Emmanuelle
Publicado no Antimicrob Agents Chemother (2016)

Population pharmacokinetics and pharmacodynamics of the artesunate–mefloquine fixed dose combination for the treatment of uncomplicated falciparum malaria in African children

Por Guidi, Monia, Mercier, Thomas, Aouri, Manel, Decosterd, Laurent A., Csajka, Chantal, Ogutu, Bernhards, Carn, Gwénaëlle, Kiechel, Jean-René
Publicado no Malar J (2019)

Fixed dose artesunate amodiaquine – a phase IIb, randomized comparative trial with non-fixed artesunate amodiaquine

Por Ogutu, Bernhards, Juma, Elizabeth, Obonyo, Charles, Jullien, Vincent, Carn, Gwenaelle, Vaillant, Michel, Taylor, Walter Robert John, Kiechel, Jean-René
Publicado no Malar J (2014)

Therapeutic efficacy of fixed dose artesunate-mefloquine for the treatment of acute, uncomplicated Plasmodium falciparum malaria in Kampong Speu, Cambodia

Por Leang, Rithea, Ros, Sakun, Duong, Socheat, Navaratnam, Visweswaran, Lim, Pharath, Ariey, Frédéric, Kiechel, Jean-René, Ménard, Didier, Taylor, Walter RJ
Publicado em 2013

Access to Artemisinin-Combination Therapy (ACT) and other Anti-Malarials: National Policy and Markets in Sierra Leone

Por Amuasi, John H., Diap, Graciela, Nguah, Samuel Blay, Karikari, Patrick, Boakye, Isaac, Jambai, Amara, Lahai, Wani Kumba, Louie, Karly S., Kiechel, Jean-Rene
Publicado em 2012

Access to artesunate-amodiaquine, quinine and other anti-malarials: policy and markets in Burundi

Por Amuasi, John H, Diap, Graciela, Blay-Nguah, Samuel, Boakye, Isaac, Karikari, Patrick E, Dismas, Baza, Karenzo, Jeanne, Nsabiyumva, Lievin, Louie, Karly S, Kiechel, Jean-René
Publicado em 2011

Tolerability and pharmacokinetics of non-fixed and fixed combinations of artesunate and amodiaquine in Malaysian healthy normal volunteers

Por Navaratnam, Visweswaran, Ramanathan, Surash, Wahab, Mohd Suhaimi Ab., Siew Hua, Gan, Mansor, Sharif Mahsufi, Kiechel, Jean-René, Vaillant, Michel, Taylor, Walter R. J., Olliaro, Piero
Publicado em 2009

The efficacy and safety of a new fixed-dose combination of amodiaquine and artesunate in young African children with acute uncomplicated Plasmodium falciparum

Por Sirima, Sodiomon B, Tiono, Alfred B, Gansané, Adama, Diarra, Amidou, Ouédraogo, Amidou, Konaté, Amadou T, Kiechel, Jean René, Morgan, Caroline C, Olliaro, Piero L, Taylor, Walter RJ
Publicado em 2009

Population pharmacokinetics of artesunate and amodiaquine in African children

Por Stepniewska, Kasia, Taylor, Walter, Sirima, Sodiomon B, Ouedraogo, Esperance B, Ouedraogo, Alphonse, Gansané, Adama, Simpson, Julie A, Morgan, Caroline C, White, Nicholas J, Kiechel, Jean-René
Publicado em 2009

The initial pharmaceutical development of an artesunate/amodiaquine oral formulation for the treatment of malaria: a public-private partnership

Por Gaudin Karen, Navaratnam Visweswaran, Ghezzoul Bellabes, Grislain Luc, Terrassin Laurent, Cuart Sylvie, Fawaz Fawaz, Caminiti Antonella, Kiechel Jean-René, Kauss Tina, Lacaze Catherine, White Nick J, Olliaro Piero L, Millet Pascal
Publicado em 2011-05-01

The initial pharmaceutical development of an artesunate/amodiaquine oral formulation for the treatment of malaria: a public-private partnership

Por Lacaze, Catherine, Kauss, Tina, Kiechel, Jean-René, Caminiti, Antonella, Fawaz, Fawaz, Terrassin, Laurent, Cuart, Sylvie, Grislain, Luc, Navaratnam, Visweswaran, Ghezzoul, Bellabes, Gaudin, Karen, White, Nick J, Olliaro, Piero L, Millet, Pascal
Publicado em 2011

Selection of Plasmodium falciparum pfcrt and pfmdr1 polymorphisms after treatment with artesunate–amodiaquine fixed dose combination or artemether–lumefantrine in Liberia

Por Otienoburu, Sabina Dahlström, Maïga-Ascofaré, Oumou, Schramm, Birgit, Jullien, Vincent, Jones, Joel J., Zolia, Yah M., Houzé, Pascal, Ashley, Elizabeth A., Kiechel, Jean-René, Guérin, Philippe J., Le Bras, Jacques, Houzé, Sandrine
Publicado no Malar J (2016)

Tolerability and safety of artesunate-amodiaquine and artemether-lumefantrine fixed dose combinations for the treatment of uncomplicated Plasmodium falciparum malaria: two open-lab...

Por Schramm, Birgit, Valeh, Parastou, Baudin, Elisabeth, Mazinda, Charles S, Smith, Richard, Pinoges, Loretxu, Sundaygar, Timothy, Zolia, Yah M, Jones, Joel J, Comte, Eric, Bruneel, Arnaud, Branger, Michel, Jullien, Vincent, Carn, Gwenaelle, Kiechel, Jean-René, Ashley, Elizabeth A, Guérin, Philippe J
Publicado em 2013

Efficacy of artesunate-amodiaquine and artemether-lumefantrine fixed-dose combinations for the treatment of uncomplicated Plasmodium falciparum malaria among children aged six to 5...

Por Schramm, Birgit, Valeh, Parastou, Baudin, Elisabeth, Mazinda, Charles S, Smith, Richard, Pinoges, Loretxu, Dhorda, Mehul, Boum, Yap, Sundaygar, Timothy, Zolia, Yah M, Jones, Joel J, Comte, Eric, Houzé, Pascal, Jullien, Vincent, Carn, Gwenaelle, Kiechel, Jean-René, Ashley, Elizabeth A, Guérin, Philippe J
Publicado em 2013

A Randomized Trial to Compare the Safety, Tolerability, and Effectiveness of 3 Antimalarial Regimens for the Prevention of Malaria in Nigerian Patients With Sickle Cell Disease

Por Olaosebikan, Rasaq, Ernest, Kolade, Bojang, Kalifa, Mokuolu, Olugbenga, Rehman, Andrea M., Affara, Muna, Nwakanma, Davis, Kiechel, Jean-René, Ogunkunle, Taofik, Olagunju, Tope, Murtala, Rukayat, Omefe, Peter, Lambe, Tosin, Bello, Surajudeen, Ibrahim, Olayinka, Olorunsola, Benedict, Ojuawo, Ayotade, Greenwood, Brian, Milligan, Paul
Publicado no J Infect Dis (2015)