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A survey of the way pharmacokinetics are reported in published phase I clinical trials, with an emphasis on oncology

OBJECTIVES: During the drug development process, phase I trials are the first occasion to study the pharmacokinetics (PK) of a drug. They are performed in healthy volunteers, or patients in oncology, and are designed to determine a safe and acceptable dose for the later phases of clinical trials. We...

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Detalhes bibliográficos
Main Authors: Comets, Emmanuelle, Zohar, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: Adis Intrnational Ltd 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799636/
https://ncbi.nlm.nih.gov/pubmed/19650677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2165/00003088-200948060-00004
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