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Glycosaminoglycan Interactions Fine-Tune Chemokine-Mediated Neutrophil Trafficking: Structural Insights and Molecular Mechanisms

Circulating neutrophils, rapidly recruited in response to microbial infection, form the first line in host defense. Humans express ~50 chemokines, of which a subset of seven chemokines, characterized by the conserved “Glu-Leu-Arg” motif, mediate neutrophil recruitment. Neutrophil-activating chemokin...

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Détails bibliographiques
Publié dans:J Histochem Cytochem
Auteurs principaux: Rajarathnam, Krishna, Sepuru, Krishna Mohan, Joseph, Prem Raj B., Sawant, Kirti V., Brown, Aaron J.
Format: Artigo
Langue:Inglês
Publié: SAGE Publications 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5958375/
https://ncbi.nlm.nih.gov/pubmed/29290145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/0022155417739864
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