Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection

Recombination in HIV-1 is well documented, but its importance in the low-diversity setting of within-host diversification is less understood. Here we develop a novel computational tool (RAPR (Recombination Analysis PRogram)) to enable a detailed view of in vivo viral recombination during early infec...

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Publicado no:Nat Commun
Main Authors: Song, Hongshuo, Giorgi, Elena E., Ganusov, Vitaly V., Cai, Fangping, Athreya, Gayathri, Yoon, Hyejin, Carja, Oana, Hora, Bhavna, Hraber, Peter, Romero-Severson, Ethan, Jiang, Chunlai, Li, Xiaojun, Wang, Shuyi, Li, Hui, Salazar-Gonzalez, Jesus F., Salazar, Maria G., Goonetilleke, Nilu, Keele, Brandon F., Montefiori, David C., Cohen, Myron S., Shaw, George M., Hahn, Beatrice H., McMichael, Andrew J., Haynes, Barton F., Korber, Bette, Bhattacharya, Tanmoy, Gao, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954121/
https://ncbi.nlm.nih.gov/pubmed/29765018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04217-5
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