Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes

Epigenetics contributes to the pathogenesis of immune-mediated diseases like rheumatoid arthritis (RA). Here we show the first comprehensive epigenomic characterization of RA fibroblast-like synoviocytes (FLS), including histone modifications (H3K27ac, H3K4me1, H3K4me3, H3K36me3, H3K27me3, and H3K9m...

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Publicado en:Nat Commun
Main Authors: Ai, Rizi, Laragione, Teresina, Hammaker, Deepa, Boyle, David L., Wildberg, Andre, Maeshima, Keisuke, Palescandolo, Emanuele, Krishna, Vinod, Pocalyko, David, Whitaker, John W., Bai, Yuchen, Nagpal, Sunil, Bachman, Kurtis E., Ainsworth, Richard I., Wang, Mengchi, Ding, Bo, Gulko, Percio S., Wang, Wei, Firestein, Gary S.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953939/
https://ncbi.nlm.nih.gov/pubmed/29765031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04310-9
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