Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes

Epigenetics contributes to the pathogenesis of immune-mediated diseases like rheumatoid arthritis (RA). Here we show the first comprehensive epigenomic characterization of RA fibroblast-like synoviocytes (FLS), including histone modifications (H3K27ac, H3K4me1, H3K4me3, H3K36me3, H3K27me3, and H3K9m...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Ai, Rizi, Laragione, Teresina, Hammaker, Deepa, Boyle, David L., Wildberg, Andre, Maeshima, Keisuke, Palescandolo, Emanuele, Krishna, Vinod, Pocalyko, David, Whitaker, John W., Bai, Yuchen, Nagpal, Sunil, Bachman, Kurtis E., Ainsworth, Richard I., Wang, Mengchi, Ding, Bo, Gulko, Percio S., Wang, Wei, Firestein, Gary S.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953939/
https://ncbi.nlm.nih.gov/pubmed/29765031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04310-9
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