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Liver X Receptor Regulates Rheumatoid Arthritis Fibroblast-like Synoviocyte Invasiveness, Matrix Metalloproteinase 2 Activation, Interleukin-6 and CXCL10

Fibroblast-like synoviocyte (FLS) invasiveness correlates with articular damage in rheumatoid arthritis (RA), yet little is known about its regulation. In this study we aimed to determine the role of the nuclear receptor liver X receptor (LXR) in FLS invasion. FLS were isolated from synovial tissues...

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Detalhes bibliográficos
Main Authors: Laragione, Teresina, Gulko, Pércio S
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459482/
https://ncbi.nlm.nih.gov/pubmed/22634718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2012.00173
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