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Liver X Receptor Regulates Rheumatoid Arthritis Fibroblast-like Synoviocyte Invasiveness, Matrix Metalloproteinase 2 Activation, Interleukin-6 and CXCL10

Fibroblast-like synoviocyte (FLS) invasiveness correlates with articular damage in rheumatoid arthritis (RA), yet little is known about its regulation. In this study we aimed to determine the role of the nuclear receptor liver X receptor (LXR) in FLS invasion. FLS were isolated from synovial tissues...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Laragione, Teresina, Gulko, Pércio S
Format: Artigo
Sprache:Inglês
Veröffentlicht: ScholarOne 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459482/
https://ncbi.nlm.nih.gov/pubmed/22634718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2012.00173
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