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Paclitaxel in tyrosine-derived nanospheres as a potential anti-cancer agent: In vivo evaluation of toxicity and efficacy in comparison with paclitaxel in Cremophor

Paclitaxel (PTX) has gained widespread clinical use yet its administration is associated with significant toxicity. In the present study, the toxicity and anti-tumor efficacy of tyrosine-derived nanospheres (NSP) for the delivery of PTX was compared to a clinical formulation of PTX in PBS-diluted Cr...

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Bibliografske podrobnosti
izdano v:Eur J Pharm Sci
Main Authors: Sheihet, Larisa, Garbuzenko, Olga B., Bushman, Jared, Gounder, Murugesan K., Minko, Tamara, Kohn, Joachim
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953571/
https://ncbi.nlm.nih.gov/pubmed/22155544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejps.2011.11.017
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