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Paclitaxel in tyrosine-derived nanospheres as a potential anti-cancer agent: In vivo evaluation of toxicity and efficacy in comparison with paclitaxel in Cremophor

Paclitaxel (PTX) has gained widespread clinical use yet its administration is associated with significant toxicity. In the present study, the toxicity and anti-tumor efficacy of tyrosine-derived nanospheres (NSP) for the delivery of PTX was compared to a clinical formulation of PTX in PBS-diluted Cr...

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Detalhes bibliográficos
Publicado no:Eur J Pharm Sci
Main Authors: Sheihet, Larisa, Garbuzenko, Olga B., Bushman, Jared, Gounder, Murugesan K., Minko, Tamara, Kohn, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953571/
https://ncbi.nlm.nih.gov/pubmed/22155544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejps.2011.11.017
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