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Polymer-Drug Interactions in Tyrosine-Derived Triblock Copolymer Nanospheres: a Computational Modeling Approach

A combination of Molecular Dynamics (MD) simulations and docking calculations was employed to model and predict polymer-drug interactions in self-assembled nanoparticles consisting of ABA-type triblock copolymers, where A-blocks are poly(ethylene glycol) units and B-blocks are low molecular weight t...

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Detalles Bibliográficos
Main Authors: Costache, Aurora D., Sheihet, Larisa, Zaveri, Krishna, Knight, Doyle D., Kohn, Joachim
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758936/
https://ncbi.nlm.nih.gov/pubmed/19650665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp900114w
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