Development of paclitaxel-TyroSpheres for topical skin treatment

A potential topical psoriasis therapy has been developed consisting of tyrosine-derived nanospheres (TyroSpheres) with encapsulated anti-proliferative paclitaxel. TyroSpheres provide enhancement of paclitaxel solubility (almost 4,000 times greater than PBS) by effective encapsulation and enable sust...

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Bibliographic Details
Main Authors: Kilfoyle, Brian E., Sheihet, Larisa, Zhang, Zheng, Laohoo, Marissa, Kohn, Joachim, Michniak-Kohn, Bozena B.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462247/
https://ncbi.nlm.nih.gov/pubmed/22732474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.06.021
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