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CREB represses transcription of fos promoter: role of phosphorylation

We have studied the regulation of protooncogene fos following serum induction. We show that un- or hypo-phosphorylated form of transcription factor cyclic AMP response element binding (CREB) protein represses the transcription of fos promoter. The negative regulation by CREB is alleviated if it is p...

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Pubblicato in:Gene Expr
Autori principali: Ofir, Rivka, Dwarki, V. J., Rashid, Dana, Verma, Inder M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cognizant Communication Corporation 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952199/
https://ncbi.nlm.nih.gov/pubmed/1840296
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